Leonard Finn, president of Charles River was invited by the Sustainable Wellesley's leadership team members, Dr. Sustainable Wellesley is an all-volunteer, nonprofit organization that engages residents, businesses and the Town of Wellesley in actions required for sustainability, including: protecting our climate reducing pollution of air, land and water preservingīiodiversity minimizing waste and ensuring environmental justice.ĭue to COVID-19, the check presentation occurred over Zoom. This year the Charles River District donated $3,000 to Sustainable Wellesley. Linda Howard, Charles River District NewsĬharles River District as part of their commitment to the communities in their catchment area- Needham, Newton, Waltham, Wellesley and Weston donate annually to a non-profit. ONLY APPLICATIONS WHICH MEET ALL THE REQUIREMENTS ARE A letter of recommendation from a district society member or a faculty member.A statement of academic standing from the medical school.
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A letter from the financial aid officer of the medical school with detailed verification of financial need.Financial information is expected to be comprehensive (this should include parents' resources).
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“Cryo-EM will expand the portfolio of drug targets that we can generate a 3D understanding of, enhance our knowledge of how to modulate these targets and enable computational drug design for more of our client projects. This leads to the identification of novel distinct binding sites and significantly improves the discovery of drug candidates.” Fast turnaround timesĭue to the minimal amount of samples needed, fast turnaround times and statistical certainty, cryo-EM will also support the analysis of adeno-associated virus (AAV) vector-based gene therapies, as well as novel mRNA and plasmid-based drugs, making it a powerful orthogonal tool to support both quality control and R&D efforts, said the companies. “Subsequently, reconstructed coulomb potential maps then allow the precise modeling of 3D atomic coordinates that elucidate the target structure. “ ATEM’s technology directly images vitrified biological macromolecules in single-particle experiments at high resolution. The alliance has the potential to significantly accelerate drug discovery efforts, according to the partners.Ĭharles River’s clients gain access to ATEM’s cryo-EM platform to support their drug discovery work, potentially getting early insights into how lead candidates interact with their intended disease target, allowing for more informed prioritization and optimization of lead candidates.